Supergirl and the team go head to head against Rama Khan and Leviathan. Meanwhile, Lena and Lex must join forces when Project Non Nocere fails, leaving the two siblings in…

Supergirl realizes that in order to stop Lex and Leviathan she must work with the one person she never thought she’d trust again – Lena. Nia keeps dreaming about Brainy…

Kara is surprised to find that CatCo has a new owner who has brought in a star reporter. New couples emerge and explore their budding relationships while J’onn J’onzz receives…

Supergirl, Alex, and Brainiac thwart an alien attack while William investigates Kara. J’onn J’onzz and Kelly use Obsidian tech to solve a problem.

Kara attempts to mend her relationship with Lena. J’onn J’onzz takes a deep dive into his memories while Kelly tries to help an old friend.

Kara’s investigation into William Dey’s “criminal” activities results in the shocking revelation he is not who she thinks. Meanwhile, the conflict between Malefic and J’onn J’onzz reaches a boiling point.

On the eve of the worldwide launch of Andrea Rojas’s VR contact lenses, Kara and William team up on an investigation that exposes a terrorist plot. Kelly and Alex celebrate…

While a new villain is under arrest at the DEO, Supergirl uses him to try and understand who is responsible for the recent attacks. Meanwhile, Andrea and Lena think back…

Supergirl finally learns the truth about Lena while tangling with Leviathan. J’onn J’onn makes a discovery about his brother’s whereabouts.

Supergirl’s struggle against Leviathan reaches a boiling point as she faces off against Rama Khan. Meanwhile, as Lena and Hope work to launch Project Non Nocere, Hope proves to be…

The Monitor sends Harbinger to gather the worlds’ greatest heroes – Supergirl, The Flash, Green Arrow, Batwoman, White Canary, The Atom and Superman – in preparation for the impending Crisis….

The subsequent complications from the Crisis leave Supergirl to face a chaotic threat.

As Supergirl tries to thwart a Toyman copycat, Winn Schott returns from the future.

Supergirl helps Winn face his greatest fear. After Alex sets out to find evidence against Lex, Brainy must decide between helping his friend or continuing to secretly work for Lex.

Mxyzptlk returns with a proposition for Kara – what if she could go back in time and tell Lena her secret before Lex did, would things turn out different? Looking…

Lex tasks Supergirl with protecting Andrea from an anti-tech extremist, but his nefarious purpose goes beyond merely keeping Andrea alive. Meanwhile, Lena moves forward with Non Nocere, with Lex’s help.

Supergirl intervenes when a building in the Heights that was set aside for low income housing is suddenly at risk to be sold to a major corporation. Supergirl recruits Orlando…

Supergirl and team must stop Nyxly from vanquishing a familiar face from Supergirl’s past – Mr. Mxyzptlk. Mxy returns and explains Nyxly’s dark history to the super team in the…

Kelly is horrified when the Ormfell building implodes, injuring many in the community, including Joey. However, her horror quickly turns to frustration when she realizes that the hospital is overwhelmed,…

Supergirl and team race Nyxly for control of a magical totem that controls courage. Supergirl and Nyxly battle and each get a piece of the totem but learn the first…

Lena is uncertain about using her magical abilities to help Supergirl retrieve the second totem from Nyxly. William struggles to write a story on the Super Friends that makes both…

Supergirl continues to fight Nyxly for the remaining totems but after Nyxly kidnaps William, Supergirl realizes she needs to take a more proactive stance to keep National City safe. Meanwhile,…

Kara lands her dream story for Catco but when the city is suddenly attacked by a nightmare monster at the same time as her interview, she is forced to take…

When Lex Luthor appears by Nyxly’s side, Supergirl and team must deal with the emotional fallout of facing their two biggest foes at the same time. Alex makes plans for…

Supergirl is determined to keep everyone safe from Lex and Nyxly so she doubles down on patrol, especially as Alex and Kelly’s bachelorette party is coming up. Alex is torn…

Supergirl and the super friends take drastic action after a loved one is kidnapped by Nyxly and Lex. An unlikely ally steps in to help the team.

Supergirl is joined by familiar faces from the past to help her stop Lex and Nyxly for good. Meanwhile, Alex and Kelly prepare to walk down the aisle.

As Brainiac lays close to death after trying to stop Lex, Supergirl and team soar in to save him, engaging in an epic battle with Gamemnae. After beating Leviathan, Supergirl…

As the stakes with Lex are raised higher than ever before, Lena must decide how far she is willing to go to stop her brother. Meanwhile, Supergirl and the team…

Supergirl makes a new ally. Lena and Lex battle for control of Luthor Corp.

Supergirl finds an opportunity to escape from the Phantom Zone but it comes with some dangerous strings attached. Meanwhile, Lena joins the Super Friends on a mission but finds she…

Nia and Brainy attempt to save Supergirl from the Phantom Zone by time traveling back to Kara’s home in 2009. While determined to secure the item needed to help Supergirl,…

As the Super Friends brave the Phantom Zone to bring Supergirl home, each member of the team is confronted by visions of their worst fear.

As Supergirl and Zor-El make their return to National City, they are determined to keep the Phantom Zone behind them and enjoy being superheroes together. Unfortunately, their overzealous efforts backfire,…

Kelly meets Joey, a young orphaned alien boy, who is acting out in foster care because he fears there is something wrong with his brother Orlando, who is incarcerated. Kelly…

When Reign starts hunting Ruby, Supergirl and Alex work together to keep her safe. Supergirl and J’onn look to Sam’s mother for advice on how to stop Reign and come…

When Tanya, a disciple of Coville’s, escapes from what’s left of his cult, she gives Kara and James a journal that could hold the key to saving Sam. Someone learns…

Supergirl is stunned to discover that a part of Krypton survived. Meanwhile, Alex is attacked while out with Ruby, and Lena considers how far she will go to keep Reign…

Kara makes a major life decision. Meanwhile, J’onn finds out that special DEO-caliber guns have hit the streets of National City.